Decoding the Valence of Developmental Social Behavior: Dopamine Governs Social Motivation Deficits in Autism
Using deep learning to automatically decode the social behavior and its valence from behavioral sequences.
Professional Summary
Xinfeng Chen (陈昕枫) is a AI Engineer at Xinqiao Hosiptal Army Medical University. He is a leading researcher in the field of AI, where he leads groundbreaking work on large language models and multimodal systems. His research has been published in top conferences like NeurIPS and ICML, with over 10,000 citations. Chen is passionate about pushing the boundaries of AI while ensuring ethical development. Outside of work, he enjoys hiking in the Rockies, building custom PCs, and mentoring the next generation of AI talent.
Education
PhD, Peking University (北京大学)
Life Science (AI Focus)
MS, Huazhong University of Science and Technology
Biomedical Engineering
BS, Huazhong University of Science and Technology
Life Science
Interests
Deep Learning
Computer Vision
Animal Behavior
Medical Imaging
📚 My Research
Key Problem: Psychiatry faces a critical barrier: psychiatric diagnosis relies on subjective human experience, lacking quantitative analysis—undermining reliability.
My Approach: To solve this, my PhD developed an AI/big data behavioral diagnostic tool (validated in rats), integrating multimodal data (behavior, vocalizations, neurotransmitter signals) and high-performance computing to outperform human analysis.
My Discoveries: The tool identified comprehensive abnormalities and diagnostic biomarkers in psychiatric model rats, and informed effective optogenetic interventions for symptom relief.
Future Plans: Noting gaps (AI’s poor generalization/interpretability; animal-human differences), I will transition to clinical research. I’ll apply my skills in device development, algorithm integration, and big data analysis to advance precise psychiatric diagnosis/treatment.
Please reach out to collaborate 😃
Featured Publications
ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance
Arduino UNO based Behavioral Platform for animal training like Go/No-Go task.
Recent Publications
(2025).
Decoding the Valence of Developmental Social Behavior: Dopamine Governs Social Motivation Deficits in Autism.
bioRxiv.
(2022).
Reward ameliorates depressive-like behaviors via inhibition of the substantia innominata to the lateral habenula projection.
Science Advances.
(2020).
Somatostatin neurons govern theta oscillations induced by salient visual signals.
Cell Reports.
(2020).
Acute continuous nocturnal light exposure decreases BSR under sevoflurane anesthesia in C57BL/6J mice: possible role of differentially spared light-sensitive pathways under anesthesia.
American Journal of Translational Research.